![The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy - ScienceDirect The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S1097276518309882-fx1.jpg)
The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy - ScienceDirect
![IRGM/Irgm1 facilitates macrophage apoptosis through ROS generation and MAPK signal transduction: Irgm1+/- mice display increases atherosclerotic plaque stability IRGM/Irgm1 facilitates macrophage apoptosis through ROS generation and MAPK signal transduction: Irgm1+/- mice display increases atherosclerotic plaque stability](https://www.thno.org/v11/p9358/toc.jpg)
IRGM/Irgm1 facilitates macrophage apoptosis through ROS generation and MAPK signal transduction: Irgm1+/- mice display increases atherosclerotic plaque stability
![Role of Mutations in NOD2/CARD15, ATG16L1, and IRGM in the Pathogenesis of Crohn's Disease | Semantic Scholar Role of Mutations in NOD2/CARD15, ATG16L1, and IRGM in the Pathogenesis of Crohn's Disease | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/aef67c5a97a382fca166e89668f42e519a6679fe/3-Figure2-1.png)
Role of Mutations in NOD2/CARD15, ATG16L1, and IRGM in the Pathogenesis of Crohn's Disease | Semantic Scholar
![IRGM promotes melanoma cell survival through autophagy and is a promising prognostic biomarker for clinical application: Molecular Therapy - Oncolytics IRGM promotes melanoma cell survival through autophagy and is a promising prognostic biomarker for clinical application: Molecular Therapy - Oncolytics](https://www.cell.com/cms/asset/2249fe34-5cf2-4dc2-978a-9e81cb9db199/fx1.jpg)
IRGM promotes melanoma cell survival through autophagy and is a promising prognostic biomarker for clinical application: Molecular Therapy - Oncolytics
![Autoimmunity gene IRGM suppresses cGAS‐STING and RIG‐I‐MAVS signaling to control interferon response | EMBO reports Autoimmunity gene IRGM suppresses cGAS‐STING and RIG‐I‐MAVS signaling to control interferon response | EMBO reports](https://www.embopress.org/cms/asset/13400fb2-ac72-460b-92c1-fa637d91081e/embr202050051-fig-0001-m.jpg)
Autoimmunity gene IRGM suppresses cGAS‐STING and RIG‐I‐MAVS signaling to control interferon response | EMBO reports
![Variants in the autophagy-related gene IRGM confer susceptibility to non-alcoholic fatty liver disease by modulating lipophagy - ScienceDirect Variants in the autophagy-related gene IRGM confer susceptibility to non-alcoholic fatty liver disease by modulating lipophagy - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0168827816303300-fx1.jpg)
Variants in the autophagy-related gene IRGM confer susceptibility to non-alcoholic fatty liver disease by modulating lipophagy - ScienceDirect
![Association of ATG16L1 and IRGM genes polymorphisms with inflammatory bowel disease: a meta-analysis approach | Genes & Immunity Association of ATG16L1 and IRGM genes polymorphisms with inflammatory bowel disease: a meta-analysis approach | Genes & Immunity](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fgene.2009.25/MediaObjects/41435_2009_Article_BFgene200925_Fig1_HTML.gif)
Association of ATG16L1 and IRGM genes polymorphisms with inflammatory bowel disease: a meta-analysis approach | Genes & Immunity
![Inhibition of IRGM establishes a robust antiviral immune state to restrict pathogenic viruses | EMBO reports Inhibition of IRGM establishes a robust antiviral immune state to restrict pathogenic viruses | EMBO reports](https://www.embopress.org/cms/asset/b651cbe6-2752-404d-ac57-5b12fb40c30f/embr202152948-abs-0001-m.jpg)
Inhibition of IRGM establishes a robust antiviral immune state to restrict pathogenic viruses | EMBO reports
![Immunity-related GTPase IRGM at the intersection of autophagy, inflammation, and tumorigenesis | Inflammation Research Immunity-related GTPase IRGM at the intersection of autophagy, inflammation, and tumorigenesis | Inflammation Research](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs00011-022-01595-x/MediaObjects/11_2022_1595_Fig2_HTML.png)
Immunity-related GTPase IRGM at the intersection of autophagy, inflammation, and tumorigenesis | Inflammation Research
![Schematic structure of the IRGM gene. A) Gene segments with lengths and... | Download Scientific Diagram Schematic structure of the IRGM gene. A) Gene segments with lengths and... | Download Scientific Diagram](https://www.researchgate.net/publication/26808300/figure/fig1/AS:310080957370368@1450940469160/Schematic-structure-of-the-IRGM-gene-A-Gene-segments-with-lengths-and-all-SNPs-that-are.png)
Schematic structure of the IRGM gene. A) Gene segments with lengths and... | Download Scientific Diagram
![Mechanism of action of the tuberculosis and Crohn disease risk factor IRGM in autophagy. - Abstract - Europe PMC Mechanism of action of the tuberculosis and Crohn disease risk factor IRGM in autophagy. - Abstract - Europe PMC](https://europepmc.org/articles/PMC4835981/bin/kaup-12-02-1084457-g001.jpg)
Mechanism of action of the tuberculosis and Crohn disease risk factor IRGM in autophagy. - Abstract - Europe PMC
![Autophagy-related IRGM genes confer susceptibility to ankylosing spondylitis in a Chinese female population: a case–control study | Genes & Immunity Autophagy-related IRGM genes confer susceptibility to ankylosing spondylitis in a Chinese female population: a case–control study | Genes & Immunity](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fgene.2016.48/MediaObjects/41435_2017_Article_BFgene201648_Fig1_HTML.jpg)
Autophagy-related IRGM genes confer susceptibility to ankylosing spondylitis in a Chinese female population: a case–control study | Genes & Immunity
![Cells | Free Full-Text | Roles of Autophagy-Related Genes in the Pathogenesis of Inflammatory Bowel Disease Cells | Free Full-Text | Roles of Autophagy-Related Genes in the Pathogenesis of Inflammatory Bowel Disease](https://www.mdpi.com/cells/cells-08-00077/article_deploy/html/images/cells-08-00077-g004-550.jpg)